|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.020 |
GeneticVariation
|
BEFREE |
We investigated the effect of the tagging single nucleotide polymorphisms (SNPs) rs1044250 (T266M) and rs116843064 (E40K) with triglyceride (TG) levels and CAD risk factors in a cohort of 220 patients undergoing coronary angiography for the evaluation of stable CAD, all of whom had (type 2 diabetes) T2D and were at least overweight.
|
27004807 |
2016 |
|
Arteriosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
We examined whether dietary macronutrient intake modified associations between ANGPTL4[E40K] variation and TG and HDL-C in White men and women from the Atherosclerosis Risk in Communities study.
|
18599063 |
2009 |
|
Atherosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
We examined whether dietary macronutrient intake modified associations between ANGPTL4[E40K] variation and TG and HDL-C in White men and women from the Atherosclerosis Risk in Communities study.
|
18599063 |
2009 |
|
Coronary heart disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
The prospective, population-based Atherosclerosis Risk in Communities Study measured the E40K ANGPTL4 variant in approximately 10000 white participants and determined its association with coronary heart disease (CHD) incidence (n = 1318 events) between 1987-1989 and 2004.
|
18940399 |
2008 |
|
Atherosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
The prospective, population-based Atherosclerosis Risk in Communities Study measured the E40K ANGPTL4 variant in approximately 10000 white participants and determined its association with coronary heart disease (CHD) incidence (n = 1318 events) between 1987-1989 and 2004.
|
18940399 |
2008 |
|
Arteriosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
The prospective, population-based Atherosclerosis Risk in Communities Study measured the E40K ANGPTL4 variant in approximately 10000 white participants and determined its association with coronary heart disease (CHD) incidence (n = 1318 events) between 1987-1989 and 2004.
|
18940399 |
2008 |
|
Obesity
|
|
0.020 |
GeneticVariation
|
BEFREE |
The objective of this study was to investigate the association of ANGPTL4 variants (E40K and T266M) with triglyceride levels and with cardiovascular risk factors, such as metabolic syndrome (MetS) and obesity in type 2 diabetic Tunisian population.
|
27004807 |
2016 |
|
Metabolic Syndrome X
|
|
0.020 |
GeneticVariation
|
BEFREE |
The objective of this study was to investigate the association of ANGPTL4 variants (E40K and T266M) with triglyceride levels and with cardiovascular risk factors, such as metabolic syndrome (MetS) and obesity in type 2 diabetic Tunisian population.
|
27004807 |
2016 |
|
Obesity
|
|
0.020 |
GeneticVariation
|
BEFREE |
The objective of this study was to determine whether ANGPTL4 E40K and T266M are associated with triglyceride levels in the setting of obesity and T2D, and whether modification of triglyceride levels by these genetic variants is altered by a lifestyle intervention designed to treat T2D.
|
21714923 |
2011 |
|
High density lipoprotein measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The impact of low-frequency and rare variants on lipid levels.
|
25961943 |
2015 |
|
Triglycerides measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The impact of low-frequency and rare variants on lipid levels.
|
25961943 |
2015 |
|
Metabolic Syndrome X
|
|
0.020 |
GeneticVariation
|
BEFREE |
The G allele at the rs116843064 polymorphic locus of the ANGPTL4 gene was associated with a lower prevalence of MetS.
|
31164103 |
2019 |
|
Cardiovascular Diseases
|
|
0.030 |
GeneticVariation
|
BEFREE |
So, T266M and E40K polymorphism predicts cardiovascular disease risk in Type 2 diabetic Tunisian population.
|
27004807 |
2016 |
|
High density lipoprotein measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
|
30698716 |
2019 |
|
Alcohol consumption
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
|
30698716 |
2019 |
|
Triglycerides measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
|
30698716 |
2019 |
|
Triglycerides measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.
|
27036123 |
2016 |
|
Arteriosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Longitudinal changes in triglycerides according to ANGPTL4[E40K] genotype and longitudinal body weight change in the atherosclerosis risk in communities study.
|
18809343 |
2008 |
|
Atherosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Longitudinal changes in triglycerides according to ANGPTL4[E40K] genotype and longitudinal body weight change in the atherosclerosis risk in communities study.
|
18809343 |
2008 |
|
RDW - Red blood cell distribution width result
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Red cell distribution width determination
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Coronary Artery Disease
|
|
0.710 |
GeneticVariation
|
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
Triglycerides measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
|
30275531 |
2018 |
|
High density lipoprotein measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.
|
30275531 |
2018 |
|
High density lipoprotein measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
|
28270201 |
2017 |